The time varies depending on the specific ED medicine. PDE5 inhibitors generally begin working within a period ranging from roughly 30 minutes to about an hour, although timing differs between medicines and individuals. Sexual stimulation is still required for an erection.

Common oral medicines for erectile dysfunction belong to the PDE5 inhibitor group. They do not produce an automatic erection; instead, they enhance the natural blood-flow response to sexual stimulation.

The timing can vary based on:

  • The specific medicine prescribed
  • Dose and individual response
  • Whether the medicine is taken with food
  • Other medications being used
  • Underlying medical conditions
  • Level of sexual stimulation

For example, sildenafil is generally taken before anticipated sexual activity, while tadalafil has a longer duration of action and may be prescribed in different dosing schedules.

If an ED tablet does not appear to work immediately, taking an additional dose without medical advice is not recommended. If the response remains inadequate, the treatment should be reviewed rather than increasing the dose independently.

PDE5 inhibitors are not appropriate for everyone, particularly men taking nitrate medicines, because of the risk of a significant drop in blood pressure.

SCI International Hospital

At SCI International Hospital, Dr. Gautam Banga can assess the underlying cause of erectile dysfunction and determine whether oral ED medication is appropriate. He can also guide patients regarding the correct medicine, timing, dosage, and alternative treatment options when tablets do not provide adequate results.

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